This page shows the details of why an item matched the keywords from your search.
| Item Type | Name |
|
Concept
|
Antineoplastic Agents, Alkylating
|
|
Academic Article
|
Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
|
|
Academic Article
|
Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases.
|
|
Academic Article
|
A phase II trial of oral temozolomide in patients with metastatic renal cell cancer.
|
|
Academic Article
|
Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells.
|
|
Academic Article
|
Temozolomide: realizing the promise and potential.
|
|
Academic Article
|
Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells.
|
|
Academic Article
|
Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
|
|
Academic Article
|
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
|
|
Academic Article
|
Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy.
|
|
Academic Article
|
Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
|
|
Academic Article
|
Increased killing of prostate, breast, colon, and lung tumor cells by the combination of inactivators of O6-alkylguanine-DNA alkyltransferase and N,N'-bis(2-chloroethyl)-N-nitrosourea.
|
|
Academic Article
|
O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.
|
|
Academic Article
|
Phase I pharmacokinetic and pharmacodynamic study of temozolomide in pediatric patients with refractory or recurrent leukemia: a Children's Oncology Group Study.
|
|
Academic Article
|
Intraarterial O6-benzylguanine enables the specific therapy of nitrosourea-resistant intracranial human glioma xenografts in athymic rats with 1,3-bis(2-chloroethyl)-1-nitrosourea.
|
|
Academic Article
|
Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies.
|
|
Academic Article
|
Modulation of cyclophosphamide activity by O6-alkylguanine-DNA alkyltransferase.
|
|
Academic Article
|
Poly(ADP-ribose) polymerase inhibitor ABT-888 potentiates the cytotoxic activity of temozolomide in leukemia cells: influence of mismatch repair status and O6-methylguanine-DNA methyltransferase activity.
|
|
Academic Article
|
Schedule-dependent activity of temozolomide plus CPT-11 against a human central nervous system tumor-derived xenograft.
|
|
Academic Article
|
O6-benzylguanine-mediated enhancement of chemotherapy.
|
|
Academic Article
|
Multicenter phase II trial of temozolomide in mycosis fungoides/sezary syndrome: correlation with O6-methylguanine-DNA methyltransferase and mismatch repair proteins.
|
|
Academic Article
|
Mechanisms of resistance to the toxicity of cyclophosphamide.
|
|
Academic Article
|
Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft.
|
|
Academic Article
|
The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
|
|
Academic Article
|
Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.
|
|
Academic Article
|
Hydroxylation and N-dechloroethylation of Ifosfamide and deuterated Ifosfamide by the human cytochrome p450s and their commonly occurring polymorphisms.
|
- Antineoplastic Agents Alkylating